Predicting carcinogenicity by using batteries of dependent short-term tests.

Predicting carcinogenicity by using batteries of dependent short-term tests.

Among the various methods for predicting carcinogenicity from a battery of short-term tests (STTs), the carcinogenicity prediction and battery selection (CPBS) procedure is the most prominent. A major assumption of CPBS is that the STTs used in the prediction are conditionally independent. Results of recent National Toxicology Program studies of four commonly used in vitro STTs contradict this ...

Do short-term tests predict rodent carcinogenicity?

Predicting short-term stock fluctuations by using processing fluency.

Three studies investigated the impact of the psychological principle of fluency (that people tend to prefer easily processed information) on short-term share price movements. In both a laboratory study and two analyses of naturalistic real-world stock market data, fluently named stocks robustly outperformed stocks with disfluent names in the short term. For example, in one study, an initial inv...

Relevance of short-term carcinogenicity tests to the study of the carcinogenic potential of urban air.

It is now accepted that screening for carcinogens in animals is expensive and demonstrates carcinogenic potential rather than actual carcinogenicity in man. A number of short-term tests which depend on mutagenicity, stimulation of DNA repair, ability to produce chromosome damage or other actions, and which correlate at least to some extent with carcinogenic potential, have been devised. These h...

Predicting Carcinogenicity

There has been an exponential growth in stress research in recent years in relation to health and employment. The formidable methodological problems confronting both epidemiological and psychobiological studies in this area have been amply demonstrated to oncologists in the difficulty of adequately testing hypotheses about the role of stress in carcinogenesis and disease progression. Some of th...